I tell them that they are not FDA cleared (except the obvious ones like insulin, the GLP-1s, etc.)
If you take oral contraceptives, antibiotics, or other time-sensitive medications, discuss timing with your prescriber
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doi: 10.1093/eurheartj/ehv320 115
Upon tissue disruption, danger-associated molecular patterns (DAMPs) Such as extracellular ATP, high-mobility group box 1 (HMGB1), and uric acid crystals are released from damaged cells [26, 27], while PAMPs from the wound microbiome including lipopolysaccharide (LPS) from Gram-negative bacteria, lipoteichoic acid from Gram-positive bacteria, and bacterial DNA-are detected by pattern recognition receptors (PRRs) such as NLRP3, AIM2, or NLRC4 [28]